Resident Evil 6
The Resident Evil series has some pretty intense fans, but this guy is just too much. He charges at you out of the darkness, picks you up, and holds you over a set of whirring fan blades. If you push the right sequence of button prompts, you can barely escape, but the creature is so hell-bent on pushing you in he’s willing to come in after you, sacrificing his body to ensure your demise. Now that’s dedication!